Clexane, whose active ingredient is enoxaparin, is an anticoagulant medication used to prevent the formation of blood clots in the body. It is mainly administered to patients who have suffered a myocardial infarction, pulmonary embolism, stroke or those who are at high risk of developing thrombosis. Enoxaparin works by decreasing the blood's ability to clot, preventing the formation of blood clots that can block arteries or veins and cause serious health complications.

Clexane Features

1. Prevention of thrombosis

One of the main functions of Clexane is to prevent the formation of blood clots in patients at risk of thrombosis. Clots can appear in deep veins (deep vein thrombosis) or break free and travel through the bloodstream to reach the lungs, heart, or other organs (pulmonary embolism, arterial embolism). These complications can be life-threatening, so the administration of enoxaparin is vital to prevent their development.

2. Treatment of cardiovascular diseases

Clexane is also used in the short-term treatment of certain acute cardiovascular diseases, such as myocardial infarction. By reducing the blood's ability to clot, it helps prevent the formation of additional clots that can block the coronary arteries and worsen the patient's clinical condition.

3. Orthopedic surgery

In patients undergoing orthopedic surgeries, such as hip or knee replacements, Clexane is administered as prophylaxis to reduce the risk of deep vein thrombus formation that could arise during the postoperative period due to immobilization and alteration in blood circulation.

Side effects of Clexane

1. Bruising

One of the most common side effects of Clexane is bruising at the injection site. This is due to the anticoagulant action of the medication, which can make it difficult for blood to clot properly after an injury. It is important to apply cold compresses to the injection area to reduce inflammation and the risk of bruising.

2. Excessive bleeding

Due to its anticoagulant action, Clexane may increase the risk of excessive bleeding, both internally and externally. It is essential that patients notify their doctor of any signs of abnormal bleeding, such as bleeding gums, unexplained bruising, or blood in urine or stool.

3. Allergic reactions

In some cases, Clexane can trigger allergic reactions in patients, ranging from mild skin rashes to anaphylaxis, a severe allergic reaction that can be life-threatening. It is crucial that those receiving this medication be under medical supervision and seek immediate attention if allergic symptoms occur, such as difficulty breathing, swelling of the face or throat, and severe dizziness.

4. Corticosteroid-induced osteoporosis

Long-term use of Clexane, especially at high doses, may increase the risk of corticosteroid-induced osteoporosis, a condition in which bones become more brittle and susceptible to fractures. It is essential that patients requiring prolonged treatment with enoxaparin are closely monitored for possible signs of osteoporosis and preventive measures taken if necessary.

5. Elevated liver enzymes

In some cases, Clexane can cause an increase in liver enzymes in the blood, indicating possible liver damage. It is essential to perform regular liver tests during treatment with enoxaparin to detect any alterations in liver function and adjust the dose of the medication if necessary.

6. Hypersensitivity

Some patients may develop hypersensitivity to enoxaparin, which is manifested by symptoms such as itching, redness, hives or swelling at the injection site. In severe cases, hypersensitivity can trigger anaphylactic shock, a life-threatening allergic reaction that requires emergency medical attention.

Conclusion

In summary, Clexane is a widely used anticoagulant medication. in the prevention and treatment of thromboembolic disorders, as well as in situations of high risk of blood clot formation. Although its effectiveness has been proven in numerous clinical studies, it is essential to be aware of the possible side effects associated with its use and maintain close medical monitoring during treatment.

Patients receiving Clexane should be aware of Watch for signs of complications, such as recurrent bruising, heavy bleeding, or allergic reactions, and contact your doctor immediately if you experience any of these symptoms. With proper supervision and regular medical follow-up, the benefits of this anticoagulant medication can outweigh the potential risks, providing vital protection against complications associated with blood clots.